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Principal Investigator: Akiko Shimamura, MD, PhD
The Shimamura Lab is seeking experienced, enthusiastic, and motivated professionals with strong scientific and organizational skills. Our laboratory is in the Division of Pediatric Hematology Oncology studies bone marrow failure and myelodysplastic syndromes. These genetic disorders are characterized by impaired blood cell production and leukemia predisposition. Research involves studying patient blood and marrow samples using genetics, biochemistry, and cell biology. Experience with induced pluripotent stem cells and hematopoiesis assays is desirable but not required. Research techniques include cell culture, plasmid preparation, cloning, qPCR, shRNA and CRISPR design, genomic DNA sequencing, DNA preps from primary patient samples, transfection of cultured cells, protein lysate preparation, western blotting, immunoprecipitation, immunofluorescence, cell survival assays, flow cytometry, methylcellulose colony assays, lentiviral vector production. We currently have a Research Fellow and Research Technologist Position open. For consideration, please send your CV to Teresa.urena@childrens.harvard.edu . |